Preheat a smoker to 275 degrees F (135 degrees C). Add hickory chips according to manufacturer’s instructions.
Combine chicken broth, melted butter, salt, and poultry seasoning in a small bowl. Inject the solution evenly throughout the breast.
Melt remaining 2 tablespoons of butter in a small dish. Brush evenly over the breast.
Combine salt, paprika, garlic powder, onion powder, and black pepper in a small bowl. Sprinkle the rub over the entire breast, making sure to coat all sides evenly.
Place breast in the preheated smoker and smoke for 3 hours or until internal temperature reaches 160 degrees F (71 degrees C). Remove from smoker and let rest for 20 minutes.
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